The SARS-CoV-2 + IIV4/PPV23 group was not inferior to the IIV4/PPV23 group in terms of seroconversion rates and GMT of influenza virus antibodies for all strains except for the seroconversion rate for the B/Yamagata strain. The seroconversion rate (100 % vs 100 %) and GMT (159.13 vs 173.20 GMT ratio of 0.92 ) of SARS-CoV-2 neutralising antibodies in the SARS-CoV-2 + IIV4/PPV23 group was not inferior to those in the SARS-CoV-2 vaccine group.
1132 participants were included in the per-protocol population (375 in the SARS-CoV-2 + IIV4/PPV23 group, 380 in the SARS-CoV-2 vaccine group, and 377 in the IIV4/PPV23 group). Results: Between March 10 and March 15, 2021, 1152 participants were recruited and randomly assigned to three groups (384 per group). Vaccines were administered 28 days apart, with blood samples taken on day 0 and day 28 before vaccination, and on day 56. Eligible participants were randomly assigned (1:1:1), using block randomization stratified, to either: SARS-CoV-2 vaccine and IIV4 followed by SARS-CoV-2 vaccine and PPV23 (SARS-CoV-2 + IIV4/PPV23 group) two doses of SARS-CoV-2 vaccine (SARS-CoV-2 vaccine group) or IIV4 followed by PPV23 (IIV4/PPV23 group). Individuals were eligible if they had no history of SARS-CoV-2 vaccine or any pneumonia vaccine and had not received an influenza vaccine during the 2020-21 influenza season. Methods: In this open-label, non-inferiority, randomised controlled trial, participants aged ≥ 18 years were recruited from the community. Barry H.Background: The safety and immunogenicity of the coadministration of an inactivated SARS-CoV-2 vaccine (Sinopharm BBIBP-CorV), quadrivalent split-virion inactivated influenza vaccine (IIV4), and 23-valent pneumococcal polysaccharide vaccine (PPV23) in adults in China is unknown. It's the world Christ lived in and the world that he redeemed.
Christians are called to be countercultural, but not anti-culture. That is one reason we launched the Biola University Center for Christianity, Culture and the Arts. He came as a physical man a man who worked with his hands as a carpenter a man who enjoyed eating and drinking with friends a Jewish man who told stories and interacted with the cultural rituals, traditions, tropes and expressions all around him. Christ didn't come as a cerebral concept or an ethereal force. The incarnation itself lends dignity to artistic and cultural pursuits. Like Advent, the arts also accept tension and welcome waiting. It is perhaps not surprising, then, that the mystery and magnitude of Advent lends itself so well to artistic exploration. It is merriment and melancholy together, beauty so sublime that, like the best art, it simultaneously comforts and rocks us to the core. Advent accepts the tension of the already and the not yet. But even as it celebrates Christ's arrival on earth and his rescue of it, Advent also looks patiently to the future return of Christ to bring all wrongs to right, once and for all. Advent celebrates the incarnation, the mind-blowing reality of the God of the universe becoming a man: living, breathing, walking on earth as we do. Advent is one of the greatest and most mysterious seasons of the Christian calendar.
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